Job Opportunities

Our Approach

We are continuously looking for smart, dynamic, and highly motivated scientists to perform groundbreaking research in biomechanics and ophthalmology.

Do not hesitate to drop us a line even though no positions are advertised!

CLOSED - Postdoctoral Fellow – Using Biomechanics to Predict Vision Loss Progression – Posted: 28 Nov 2013

Job description: We are looking for a bright, dynamic, and highly motivated individual to perform research in biomechanics with applications to ophthalmology. This is a project in collaboration with clinicians from the Singapore Eye Research Institute (top 5 eye institute worldwide) and from Moorfields Eye Hospital, London, UK (biggest eye hospital worldwide).

The proposed study aims to predict vision loss progression from glaucoma – a blinding ocular disorder for which mechanisms are far from being understood. Glaucoma is characterized by cell loss within the optic nerve head (ONH) at the back of the eye. Our recent work suggested that cellular death could be the result of a biomechanically deficient ONH. Thus we hypothesize that in-vivo measurements of ONH biomechanics can be used to predict vision loss progression. To test such hypothesis, the successful candidate is expected to contribute to a longitudinal study, in which ONH biomechanics and vision performance will be continuously quantified over a period of 2 years in glaucoma patients and naturally-ocurring ocular-hypertensive primates at high risk of vision loss progression. The strength of this work lies in the combined use of state-of-the-art biomechanical tools and carefully selected at-risk populations.

This project is in collaboration with Dr Linbo Liu from NTU who will provide the Enhanced Sensitivity OCT device and with Prof Aung Tin from the Singapore Eye Research Institute who will provide clinical feedback.

Specifically, the successful candidate will use, improve and develop 3D image tracking algorithms to compute pressure-induced strains/stresses within the ONH tissues given 3D optical coherence tomography volumes of eyes of patients and primates. As this is a longitudinal study, growth and remodeling of the ONH connective tissues tissues will also be investigated.

Biomechanical studies of the ONH are to date limited to ex-vivo testing or computational modeling. This study aims to propose novel techniques to quantify ONH biomechanics in vivo, and to apply them longitudinally in at-risk populations. Given the alarming cost of blindness, findings from this study could translate into novel glaucoma diagnosis tools and drive the development of novel therapies.

Qualification: Excellent programming skills (in C/C++ and Java or Matlab) and knowledge of 3D image tracking techniques (e.g. digital volume correlation, particle image velocimetry) are required. The candidate is also expected to have knowledge of nonlinear continuum mechanics and the finite element method. Knowledge of the Virtual Fields Method, code parallelization, and optical coherence tomography is considered a plus. Hands-on experience in mechanical or biomechanical testing is also considered a plus. No background in ophthalmology is required. Candidates with PhD in Biomedical Engineering, Computer Science, Mechanical Engineering, Civil Engineering, or other related disciplines are encouraged to apply.

Starting Date: March 2014.

Duration: 2-3 years.

To apply, please email a detailed CV, and the names of two references to:

Dr. Michael JA Girard
In vivo Biomechanics Laboratory
Department of Bioengineering
National University of Singapore
Email: jobs@invivobiomechanics.com

CLOSED - Research Assistant – Ophthalmic Imaging using Enhanced Sensitivity OCT - Posted: 17 Jun 2013

Position: Research Assistant – Ophthalmic Imaging using Enhanced Sensitivity Optical Coherence Tomography - Posted: 17 Jun 2013

Job description: We are looking for a bright, dynamic, and highly motivated individual to perform research in bioimaging and biomechanics with applications to ophthalmology. We have received funding to build and design a novel optical coherence tomography (OCT; a 3D medical imaging modality) device with enhanced sensitivity.

The successful candidate will test and evaluate the ability of such device to fully visualize the structures of the optic nerve head (located at the back of the eye) under varying eye pressure (ex-vivo experiments). This novel OCT device has strong potential to help us diagnose and manage blinding ocular disorders that damage the optic nerve head (e.g. glaucoma).

This project is in collaboration with Dr Linbo Liu from NTU who will provide the Enhanced Sensitivity OCT device and with Prof Aung Tin from the Singapore Eye Research Institute who will provide clinical feedback.

Qualification: Very good image processing skills are required (e.g. in Matlab or C/C++). Hands-on experience with biological tissues (e.g. for biomechanical or bioimaging experiments) is also required. No prior background in ophthalmology is required. Candidates with BSc degrees in Biomedical Engineering, Computer Science, Mechanical Engineering, Civil Engineering, or other related disciplines are encouraged to apply.

Starting Date: January 2014.

Duration: 6-12 months.

To apply, please email a detailed CV, and the names of two references to:

Dr. Michael JA Girard
In vivo Biomechanics Laboratory
Department of Bioengineering
National University of Singapore
Email: jobs@invivobiomechanics.com

POSITION FILLED Research Assistant – Image Processing in Ophthalmology - Posted: 17 Jun 2013

Position: Research Assistant – Image Processing in Ophthalmology - Posted: 17 Jun 2013

Job description: We are looking for a bright, dynamic, and highly motivated individual to perform research in image processing with applications to ophthalmology.

The successful candidate will be involved in 2 projects. First, s/he will develop automated detection algorithms to identify iris textures given 2D images of the iris. Second, the successful candidate will develop techniques to quantify the morphology of the lamina cribrosa (the main site of damage in glaucoma) using 3D optical coherence tomography images of patients’ eyes. Proper morphometric analysis of the iris and lamina cribrosa could prove crucial in the diagnosis and risk management of glaucoma, a leading cause of blindness in Asians.

This project is in collaboration with Dr Cheng Ching-Yu from the Singapore Eye Research Institute who will provide medical images from patients and will also provide clinical feedback on the developed algorithms.

Qualification: Very good programming and image processing skills (2D and 3D) are required (e.g. in Matlab, C/C++, Java). Knowledge of high-level 3D visualization software (e.g. Amira, Avizo, Mimics) is considered a plus. No prior background in ophthalmology is required. Candidates with degrees in Biomedical Engineering, Computer Science, Mechanical Engineering, Civil Engineering, or other related disciplines are encouraged to apply.

Starting Date: August 2013.

Duration: 12 months.

To apply, please email a detailed CV, and the names of two references to:

Dr. Michael JA Girard
In vivo Biomechanics Laboratory
Department of Bioengineering
National University of Singapore
Email: jobs@invivobiomechanics.com

POSITION FILLED Research Associate/Postdoctoral Fellow - In Vivo Corneal Biomechanics - Posted: 06 Nov 2012

Position: Research Associate/Postdoctoral Fellow - In Vivo Corneal Biomechanics - Posted: 06 Nov 2012

Job description: We are looking for a smart, dynamic, and highly motivated individual with a PhD to perform groundbreaking research in biomechanics with applications to ophthalmology. We are currently developing engineering tools for the diagnosis and therapy of ocular disorders (e.g. glaucoma and myopia). For more information regarding our In Vivo Biomechanics Laboratory, please visit http://www.bioeng.nus.edu.sg/ivb.

The successful candidate will use and help develop algorithms to quantify the biomechanics of the cornea in vivo. 3D images of patients’ corneas captured with optical coherence tomography will be provided. We are hoping to use such algorithms in clinic for the diagnosis of corneal disorders and glaucoma. The candidate will be able to interact with clinicians from Moorfields Eye Hospital (biggest eye hospital worldwide located in London UK) and the Singapore Eye Research Institute (top 5 eye institute worldwide).

Qualification: Excellent programming skills are required (Matlab and C/C++). Knowledge of the finite element method (nonlinear analysis) and 3D image tracking techniques (i.e. digital volume correlation or particle image velocimetry) is considered a strong advantage. Hands-on experience in mechanical and/or biomechanical testing is also considered a plus. No prior background in ophthalmology is required. Candidates with PhD degrees in Computer Science, Mechanical Engineering, Civil Engineering, or other related disciplines are encouraged to apply.

This is a 1 year contract and the estimated starting date is Jan 2013. This post will remain online until the position is filled.

To apply, please email a detailed CV, and two reference letters to:

Dr. Michael JA Girard
In vivo Biomechanics Laboratory
Department of Bioengineering
National University of Singapore
Email: jobs@invivobiomechanics.com

POSITION FILLED Joint International PhD Opportunity in Glaucoma, Imperial-NUS PhD Scholarship - Posted: 22 Nov 2012

Position: We are searching for a suitable candidate to join an application for a joint international 4-year PhD studentship between Imperial College London and the National University of Singapore, in collaboration with the Georgia Tech Institute of Technology, USA. If the application is successful the student can expect to start in September 2013. The first two years of the project will be spent at Imperial College London in the UK, and the second two at NUS in Singapore.

Description: The proposed study will investigate the structural and mechanical basis of glaucoma. A common ophthalmic disease, glaucoma is the second leading cause of blindness worldwide. The World Health Organisation has estimated that globally there are 12.5 million people blind from glaucoma with the total number affected by this condition around 66 million. In Singapore and the UK the disease accounts for approximately 40% and 10% of blindness respectively. The condition often arises when the internal (intraocular) pressure of the eye rises in old age, distorting the shape of the optic nerve. Our aim is to understand how the resulting biomechanical insult at the level of the lamina cribrosa leads to vision loss. Specifically the objectives are to (i) measure the deformations of the lamina cribrosa in whole human eyes due to increases in IOP. Such work will allow us (ii) to fully quantify the biomechanical environment (stresses, strains) within the lamina cribrosa. Then (iii) investigate whether deformations in the lamina cribrosa compress, distort or damage the retinal nerves. Tissue structure will be quantified using a novel 3D micro-CT based approach. Strains and stresses will be quantified using digital volume correlation and the finite element method.

Qualification: The proposed PhD student will be required to actively participate in writing the research proposal and online application forms. The deadline for submission of the proposal is January 25th 2013. As such the project would suit a postgraduate with a strong engineering background, or medic or biologist (with skills in numerical methods) interested in studying the role of human tissue structure and function in disease. No prior knowledge of ophthalmology is required.

There has been good success in past studentship competitions, i.e. a large fraction of applicants are awarded studentships.

For Further details please contact Richard Abel (Richard.abel@imperial.ac.uk) or Michaël Girard (mgirard@nus.edu.sg).

For more information about our research please visit:
http://www1.imperial.ac.uk/medicine/people/richard.abel/
http://www.bioeng.nus.edu.sg/ivb
http://www.ibb.gatech.edu/ross-ethier

For more information about the scholarship please visit:
http://www3.imperial.ac.uk/international/prospective/phds/nus/funding

Dr Richard Abel (Lecturer, Imperial College)
Dr Michaël Girard (Assistant Professor, NUS)
Prof. Ross Ethier (Professor, Georgia Institute of Technology)

PhD Applicants

To perform a PhD in our laboratory, students need to apply through the NUS scholarship system. Please contact us before submission of your application as we will be able to advise you about the process.

Apply for NUS Scholarship


International students can also apply for a Singapore International Graduate Award (AWARD). Our projects are listed on this page under Faculty of Engineering >> Department of Bioengineering. Interested students can list such projects as their preferred projects.

Apply for SINGA


Students can also apply for an Imperial-NUS PhD Scholarship where 2 years will be spent at Imperial College London and 2 years at NUS. The PI (Girard) has strong links with Imperial College London as he spents 3 years of his career as a Research Fellow from 2009 to 2012 in the the Department of Bioengineering. Multiple research projects in collaborations with outstanding scientists from Imperial College London can therefore be easily identified. Any serious applicant should contact us before starting an application.

Apply for Imperial College - NUS Scholarship

Postdoctoral Applicants

PhD holders should refer to the NUS websites for job opportunities in our laboratory. We also encourage young PhDs to look for scholarship and fellowship opportunities (see below). We can sponsor such applications.


For citizens or legal residents of the US:

Whitaker Scholar Grant


Self-funded Applicants

We welcome self-funded applicants (based in Singapore or Abroad) to perform research in biomechanics and ophthalmology. The applicants should contact us to discuss ideas and directions for projects.

Other Applicants

We are interested in hiring research assistants, laboratory technicians, high level programmers, etc. The candidates should refer to the NUS websites for job opportunities in our laboratory.