Members

Principal Investigator

Michaël J.A. Girard, PhD

Biography

Dr Michael Girard is an Assistant Professor in the Department of Biomedical Engineering at the National University of Singapore (NUS) and the Co-Head of the Bioengineering & Devices Research Group at the Singapore Eye Research Institute (SERI). Dr Girard received his engineering diploma (equivalent to a MSc) in Mechanical Engineering from the Ecole Polytechnique Universitaire de Lyon, France in 2003. He was awarded his PhD from the Department of Biomedical Engineering at Tulane University, New Orleans, USA, in January of 2009. Subsequently, Dr Girard pursued his postdoctoral work in the Department of Bioengineering at Imperial College London, UK. In September of 2010, Dr Girard was awarded a highly competitive and prestigious Imperial College Junior Research Fellowship to pursue his research. Throughout his training, Dr Girard has gained expertise in experimental, theoretical, and computational soft tissue biomechanics, which he has utilised to pose and answer questions of high clinical relevance in the field of ophthalmology.

Dr Girard's current research program aims to develop state-of-the-art engineering tools for the diagnosis and treatment of biomechanically-related pathologies.



Postdoctoral Fellows


Zhang Liang, PhD


Biography

Zhang Liang is a Research Fellow in the Department of Biomedical Engineering at the National University of Singapore (NUS).

Liang received his BEng in Engineering Science Program from NUS in July 2013. Upon graduation, Liang accepted the NGS (NUS Graduate School for Integrative Science and Engineering) Ph.D. scholarship at NUS. During his Ph.D. study, he investigated ocular biomechanics through computational techniques for the purpose of glaucoma diagnosis and prognosis. Computational techniques used include finite element method, virtual fields method, differential evolution, and digital image correlation. In December 2017, Liang was conferred his Ph.D.

Currently, Liang is working on the diagnosis of glaucoma from multi-device, multi-ethnicity clinical images using deep learning (AI) models.


Rosmin Elsa Mohan, PhD


Biography

Rosmin is a Research Fellow in the Department of Biomedical Engineering at the National University of Singapore (NUS) and an Adjunct Research Fellow at the Singapore Eye Research Institute (SERI).

She joined NUS after her postdoc at Nanyang Technological University, Singapore and a PhD from India. She did her PhD in nonlinear optics studying propagation of solitons in planar waveguides from Amrita University, India. Her work at NTU was on phase retrieval using interferometric and non interferometric optical setups for optical metrology and biomedical applications.

Her current research interests at NUS include setting up a Low Coherence Tissue Interferometry setup and a 3 beam Optical Coherence Tomography setup for 3D imaging of the ocular layers in collaboration with the Singapore Eye Research Institute.



PhD Candidates


David Tan, BEng


Biography

David is currently a PhD candidate in the department of Biomedical Engineering at the National University of Singapore. He received his BEng in Biomedical Engineering from NUS in year 2014.

He is currently working on the a project aimed at identifying mechanical properties of the cornea in-vivo through the use of inverse finite element. His final year BEng project was titled the "Finite Element Modelling of Cornea Biomechanics".


Than Chuangsuwanich, BEng


Biography

Thanadet is currently a PhD candidate in the Department of Biomedical Engineering, National University of Singapore.

Thanadet received is BEng in Biomedical Engineering from NUS in 2014.

He is now working on a computational model to study blood flow and oxygen diffusion in the micro-capillary network of the lamina cribrosa. He believes that the development of a comprehensive model would greatly enhance our understanding of open-angle glaucoma pathophysiology.


Royston Tan, BEng


Biography

Royston is currently a PhD candidate in the Department of Biomedical Engineering, National University of Singapore (NUS). He received his BEng in Biomedical Engineering from NUS in 2015.

He is currently working on projects involving medical devices in the field of ophthalmology, collaborating with clinicians from SERI and NUHS to develop them. His work involves design and fabrication of devices, validating them with experimental, theoretical and computational data.


Tin A Tun, MBBS, MSc


Biography

Dr Tun is a part-time PhD candidate in the department of Biomedical Engineering at the National University of Singapore. He graduated from the University of Medicine (1), Myanmar (2005) and received his MSc in Biomedical Engineering from the Nanyang Technological University in 2007.

Tun has pursued medical research in a full-time manner and involved in optical imaging projects related to glaucoma. He is currently attempting to characterize the morphology of lamina cribrosa and peripapillary sclera.


Devalla Sripad, B.Tech


Biography

Devalla Sripad is currently a PhD student in the Department of Biomedical Engineering at the National University of Singapore. He received his B.Tech. in Electrical and Electronics Engineering from National Institute of Technology Trichy,India(2012-2016).

He had been working in the field of robotics,extensively in domains such as control systems, hardware design and image processing.

He is currently working on developing novel compensation and staining techniques to improve the quality of OCT images.


Liam Fisher, BEng


Biography

Liam is a PhD candidate at the NUS Graduate School of Integrative Sciences and Engineering (NGS). He received his Bachelor of Engineering from the NUS Department of Biomedical Engineering in 2016.

His research interests include nonlinear solid mechanics and finite element analysis. Currently he is attempting to characterise the biomechanics of eye movements and the associated deformation of the optic nerve, potentially establishing links to glaucoma and other ocular pathologies.


Jin Yuejiao, BEng


Biography

Yuejiao is currently an NGS (NUS Graduate School for Integrative Science and Engineering) scholar at the National University of Singapore. She received her BEng in Engineering Science Program from NUS in July 2016.

Yuejiao has been working in the field of photonics and optics during her undergraduate study. She is currently working on a computational model to study the biomechanics of the ocular pulse.


Haris Cheong, BEng


Biography

Haris is currently a PhD student in the Department of Biomedical Engineering at the National University of Singapore (NUS). He received his Bachelor's in Biomedical Engineering from NUS in 2016.

Currently, Haris is working on using Artificial Intelligence to process and enhance Optical Coherence Tomography images.


Satish Kumar Panda, MTech


Biography

Satish is currently a PhD candidate in the Department of Biomedical Engineering at the National University of Singapore.

Prior to NUS, he had obtained a Master's degree in applied mechanics (IIT Delhi, India-TU Darmstadt, Germany) and a Bachelor's degree in mechanical engineering (NIT Durgapur, India). In addition, he has 4 years of R&D experience in various automotive industries.

His area of research interest lies in electromechanics and soft tissue modelling. He is currently working on Artificial Intelligence and Biomechanics for Improved Glaucoma Diagnosis.


Sylvi F. R. Irnadiastputri, BEng


Biography

Sylvi is a PhD student in the Department of Biomedical Engineering at the National University of Singapore (NUS). She received her Bachelor's in Biomedical Engineering from NUS in 2018.

She is currently working on a computational model to study the effects of aging and blood pressure on intraocular pressure, potentially establishing links to glaucoma.



Research Engineer


Pham Tan Hung, BEng


Biography

Hung is currently a Research Engineer in the Department of Biomedical Engineering at National University of Singapore (NUS). He is concurrently pursuing a master in Computing – Computer Science Specialisation.

Hung received his BEng in Biomedical Engineering with minor in Computer Science from NUS in 2017.

With his interest and knowledge in both Biomedical and Computer Science, he is now working on developing a novel automated iris grading system for quantitative iris surface features analysis.


Chin Zhi Yun, BEng


Biography

Zhi Yun is currently a Research Engineer in the Department of Biomedical Engineering at National University of Singapore (NUS).

Zhi Yun received her BEng in Biomedical Engineering from NUS in 2015. During her Final Year Project, she had worked on the quantitative mapping of collagen fibre orgranization in porcine eyes using small angle light scattering.



Lab Alumni


Sri Gowtham Thakku, BEng


Biography

Gowtham was a Research Assistant jointly appointed by the Singapore Eye Research Institute (SERI) and the Department of Biomedical Engineering, National University of Singapore (NUS).

He graduated with a degree in Mechanical Engineering from NUS (2013) and is currently working on two projects, both aimed at identifying biomarkers for glaucoma, but each looking at a different region within the eye. By applying image processing techniques, he is attempting to characterize features of the iris and lamina cribrosa, two structures whose morphologies are hypothesized to correlate with glaucoma. Successful identification of such morphologic characteristics holds potential for early glaucoma screening and diagnosis.

Gowtham’s interest in the biomedical sciences stems from a class on moral philosophy he took, and a subsequent summer program in bioethics he did as an undergraduate. His final year thesis was titled “Detection of Knee Hyperextension using Wearable Inertial Sensors”.

William Cheuk Wang Chung, PhD

Biography

William was a Postdoctoral Fellow in the Department of Biomedical Engineering at the National University of Singapore (NUS).

William received his BEng (Mechanical Engineering, with Honours 2nd Class Upper), MSc (Bioinformatics) and PhD from NUS. He was the recipient for both the NUS-BII scholarship (2003-2005) and the NUS Research Scholarship (2007-2011).

Throughout his career, William has acquired knowledge and experience in bioinformatics, experimental work, and computational modelling. He has developed algorithms to discover biological pathways, and has built devices and mathematical models to investigate the mechanical properties of soft tissues.

William is currently developing computational techniques to quantify corneal deformation and enhance OCT images obtained from patients with corneal defect. He is also investigating the microstructure of peripapillary sclera and lamina cribrosa in porcine eye using small-angle light scattering (SALS) technique. Part of his work was presented in the 15th International Conference on Biomedical Engineering, Singapore.

Khai Sing Chin, MSc

Biography

Ms Chin was a Research Engineer in the Department of Biomedical Engineering at the National University of Singapore. She received a B.Eng in Bioengineering from NTU (2005-2009) and a MPhil in Computing from the University of Dundee, UK (2010-2012).

Ms Chin's research interests include Biomedical Engineering and Medical Image Processing.

Ms Chin has helped developed techniques to perform compensation, automated segmentation, and 3D deformation tracking of the optic nerve head tissues from optical coherence tomography images.


Meghna Rakesh Beotra, BE

Biography

Meghna was a PhD student in the Department of Biomedical Engineering at the National University of Singapore. She received her B.E. in Biomedical Engineering from Manipal Institute of Technology, Manipal University, India (2009-2013).

With the knowledge of Tissue Biomechanics and Medical Image Processing acquired during her bachelors, she is currently working on techniques to image the optic nerve head tissues (ex-vivo) and looks forward to image these tissues in vivo and track laminar deformation.


Xiaofei Wang, PhD


Biography

Xiaofei was a Postdoctoral Fellow in the Department of Biomedical Engineering at the National University of Singapore (NUS).

Xiaofei received his bachelor’s degree in underground engineering from Central South University, China (2008) and his Master’s degree in structural engineering from Dalian University of Technology, China (2011). He obtained his PhD degree in 2014 from the University of New South Wales, Australia. During his PhD, he explored the possible causes of bitemporal hemianopia by investigating the biomechanics of optic chiasmal compression.

Xiaofei’s current research interests include, but are not limited to, the biomechanics of nerve compression, eye movement and image processing.



Projects

Finite Element Analysis and Eye Movements

3D Tracking of Optic Nerve Head

Experimental Ocular Biomechanics

Quantitative mapping of collagen fibre organization in human donor eyes

Bruch’s membrane biomechanics

Novel Therapy for Strabismus

Development of a Ring Implant for Glaucoma

Experiments and computational modeling to optimize pupil expander shapes

Development of Smart Glaucoma Drainage Devices

Finite Element Modelling of Lamina Cribrosa Blood Flow

Finite Element Modelling of Corneal Biomechanics

Finite Element Modelling of Iris Biomechanics

Quantitative mapping of collagen fibre organization using small angle light scattering

Development of a Novel Photosensitive Glaucoma Implant

Quantitative mapping of collagen fibre organization using small angle light scattering

Finite Element Modelling of Corneal Biomechanics

Segmentation of Optical Coherence Tomography Images of the Optic Nerve Head

Fabrication of a Pressure Chamber for Inflating Ex-vivo Eyes

Microstructural Finite Element Modelling of Optic Nerve Head Biomechanics

Segmentation of Optical Coherence Tomography Images of the Optic Nerve Head

Development of Biomechanically-based Therapies for Myopia and Glaucoma

Development of a Novel Technique to Characterise Corneal Biomechanics In Vivo

Finite Element Modelling of Extraocular Muscles

Academic Year

Summer 2016

Summer 2016

Summer 2016

2015 - 2016

2015 - 2016

2015 - 2016

2015 - 2016

2014 - 2015

2014 - 2015

2014 - 2015

2014 - 2015

2014 - 2015

2014 - 2015

2013 - 2014

2013 - 2014

2013 - 2014

2013 - 2014

Summer 2013

2012 - 2013

2012 - 2013

2012 - 2013

2012 - 2013

2012 - 2013