Microhemodynamics Laboratory

Journal Publications, Peer-Reviewed

Published and accepted

Copyright Notice:
The publishers hold the copyright of these articles. The PDFs are provided here to ensure rapid dissemination of scholarly work. It is understood that you will use them only in a manner consistent with the fair-use provisions of the relevant copyright laws. You may not distribute them or use them for any commercial enterprise.

2017

Tan, J.K., Park, S.Y., Leo, H.L. and Kim, S., 2017. Continuous Separation of White Blood Cells From Whole Blood Using Viscoelastic Effects. IEEE Transactions on Biomedical Circuits and Systems.

Meongkeun Ju, Hwa Liang Leo and Sangho Kim, Numerical investigation on red blood cell dynamics in microflow: Effect of cell deformability, Clinical Hemorheology and Microcirculation, 65, 105-117. PDF

Srinivasu Valagerahally Puttaswamy, Qiongfeng Shi, Aishwarya Bandla, Sangho Kim, Nitish V. Thakor, and Chengkuo Lee, Nanowire Electrodes Integrated on Tip of Microwire for Peripheral Nerve Stimulation, Journal of Microelecrtomechanical Systems. PDF

2016

Bumseok Namgung, Justin Kok Soon Tan, Peter Agustinus Wong, Sung-Yong Park, Hwa Liang Leo, and Sangho Kim, Biomimetic Precapillary Flow Patterns for Enhancing Blood Plasma Separation: A Preliminary Study, Sensors. PDF

Yan Cheng Ng, Bumseok Namgung, Sim Leng Tien, Hwa Liang Leo, and Sangho Kim, Symmetry recovery of cell-free layer after bifurcations of small arterioles in reduced flow conditions: Effect of RBC aggregation, AJP Heart and Circulatory Physiology. PDF

Yan Cheng Ng, Liam K. Fisher, Veena Salim, Sangho Kim, and Bumseok Namgung, Visualization and quantification of cell-free layer in arterioles of the rat cremaster muscle, Journal of Visualized Experiments (JoVE). Video article

Jeonghun Nam, Yong Shin, Justin Tan, and Sangho Kim, High-throughput malaria parasite separation using a viscoelastic fluid for ultrasensitive PCR, Lab on a Chip, 16(11), 2016. PDF

Swe Soe Ye, Meongkeun Ju, and Sangho Kim, Recovery of cell-free layer and wall shear stress profile symmetry downstream of an arteriolar bifurcation, Microvascular Research, 106, 14–23, 2016. PDF

Qing Liu, Jeonghun Nam, Sangho Kim, Chwee Teck Lim, Mi Kyoung Park, and Yong Shin, Two-stage sample-to-answer system based on nucleic acid amplification approach for detection of malaria parasites, Biosensors and Bioelectronics, 82, 1–8, 2016. PDF

2015

Yan Cheng Ng*, Bumseok Namgung*, Hwa Liang Leo, and Sangho Kim, Erythrocyte aggregation may promote uneven spatial distribution of NO/O2 in the downstream vessel of arteriolar bifurcations, Journal of Biomechanics, 2015. PDF

Jeonghun Nam, Justin Tan, Bee Luan Khoo, Bumseok Namgung, Hwa Liang Leo, Chwee Teck Lim, Sangho Kim, Hybrid capillary-inserted microfluidic device for sheathless particle focusing and separation in viscoelastic flow, Biomicrofluidics, 9(6), 064117, 2015. PDF

Bumseok Namgung*, Yan Cheng Ng*, Jeonghun Nam, Hwa Liang Leo, and Sangho Kim, Alteration of Blood Flow in a Venular Network by Infusion of Dextran 500: Evaluation with a Laser Speckle Contrast Imaging System, PLoS One, 10 (10): e0140038. doi:10.1371/journal.pone.0140038, 2015. PDF

Jeonghun Nam*, Bumseok Namgung*, Chwee Teck Lim, Jung-Eun Baec, Hwa Liang Leo, Kwang Soo Choc, and Sangho Kim, Microfluidic device for sheathless particle focusing and separation using a viscoelastic fluid, Journal of Chromatography A, 1406, 244-250, 2015. PDF

Yan Cheng Ng*, Bumseok Namgung*, and Sangho Kim, Two-dimensional transient model for prediction of arteriolar NO/O2 modulation by spatiotemporal variations in cell-free layer width, Microvascular Research, 97, 88-97, 2015. PDF

Seungkwan Cho, Bumseok Namgung, Han Sung Kim, Hwa Liang Leo and Sangho Kim, Effect of erythrocyte aggregation at pathological levels on NO/O2 transport in small arterioles, Clinical Hemorheology and Microcirculation, 59, 163-175, 2015. PDF

2014

Bumseok Namgung, Hiromi Sakai, and Sangho Kim, Influence of erythrocyte at pathological levels on cell-free marginal layer in a narrow circular tube, Clinical Hemorheology and Microcirculation, DOI: 10.3233/CH-141909, 2014. (Pre-Press) PDF

Bumseok Namgung, and Sangho Kim, Effect of uneven red cell influx on formation of cell-free layer in small venules, Microvascular Research, DOI: 10.1016/j.mvr.2014.01.007, 2014. PDF

Hong Tong Low, Meongkeun Ju, Yi Sui, Tayyab Nazir, Bumseok Namgung, and Sangho Kim, Numerical simulations of deformation and aggregation of red blood cells in shear flow, Critical Reviews in Biomedical Engineering, DOI: 10.1615/CritRevBiomedEng.2014010689, 2014

Swe Soe Ye, Yan Cheng Ng, Justin Kok Soon Tan, Hwa Liang Leo, and Sangho Kim, Two-dimensional strain-hardening membrane model for large deformation behavior of multiple red blood cells in high shear conditions, Theoretical Biology and Medical Modelling, 11(19), doi: 10.1186/1742-4682-11-19, 2014 PDF

2013

Bumseok Namgung, Leo Hwa Liang, and Sangho Kim, Chapter 4: Physiological significance of cell-free layer and experimental determination of its width in microcirculatory vessels, Visualization and simulations of complex flows in biomedical engineering, Springer, ISBN 9789400777682, 12, 75-87, 2013. PDF

Seungkwan Cho, Swe Soe Ye, Hwa Lian Leo and Sangho Kim, Chapter 5: Computational simulation of NO/O2 transport in arterioles: Role of cell-free layer, Visualization and simulations of complex flows in biomedical engineering, Springer, ISBN 9789400777682, 12, 89-100, 2013. PDF

Meongkeun Ju, Swe Soe Ye, Bumseok Namgung, Seungkwan Cho, Hon Tong Low, Hwa Liang Leo, and Sangho Kim, A review of numerical methods for red blood cell flow simulation, Computer Methods in Biomechanics and Biomedical Engineering, DOI 10.1080/10255842.2013.783574, 2013. PDF

Peng Kai Ong, and Sangho Kim, Effect of erythrocyte aggregation on spatiotemporal variations in cell-free layer formation near on arteriolar bifurcation, Microcirculation, 20(5), 440-453, 2013. PDF

Bumseok Namgung, Peng Kai Ong, and Sangho Kim, Effect of low molecular weight dextran on erythrocyte aggregation, Macromolecular Research, 21(9), 1042-1044, 2013. PDF

Meongkeun Ju, Swe Soe Ye, Hong Tong Low, Junfeng Zhang, Pedro Cabrales, Hwa Liang Leo, and Sangho Kim, Effect of deformability difference between two erythrocytes on their aggregation. Physical Biology, 10(3):036001, DOI 10.1088/1478-3975/10/3/036001, 2013. PDF

Bumseok Namgung, Meongkeun Ju, Pedro Cabrales, and Sangho Kim, Two-phase model for prediction of cell-free layer width in blood flow, Microvascular Research, 85(1), 68-76, 2013. PDF

2012

Peng Kai Ong, Swati Jain, and Sangho Kim, Spatio-temporal variations in cell-free layer formation near bifurcations of small arterioles, Microvascular Research, 83(2), 118-125, 2012. PDF

Meongkeun Ju, Bumseok Namgung, and Sangho Kim, Application of Refutas model to estimate erythrocyte viscosity in a dextran solution, Macromolecular Research, 20(8), 887-890, 2012. PDF

Peng Kai Ong, Swati Jain, Bumseok Namgung, Sangho Kim, Keyoung Jin Chun and Dohyung Lim, Study of time-dependent characteristics of a syllectogram in the presence of aggregation inhibition, International Journal of Precision Engineering and Manufacturing, 13(3), 421-428, 2012. PDF

Peng Kai Ong, Seungkwan Cho, Bumseok Namgung, and Sangho Kim, Effects of cell-free layer formation on NO/O2 bioavailability in small arterioles, Microvascular Research, 83(2), 168-177, 2012. PDF

Joo Hyung Lee, Keyong Jin Chun, Han Sung Kim, Sangho Kim, Kwon-Young Lee, Dae Jun Kim, and Dohyung Lim, Changes in microarchitectural characteristics at the tibial epiphysis induced by collagen-induced rheumatoid arthritis over time, Clinical Interventions in Aging, 7, 373-382, 2012. PDF

Joo Hyung Lee, Keyong Jin Chun, Han Sung Kim, Sangho Kim, Paul Han, Yongtae Jun, and Dohyung Lim, Alteration patterns of trabecular bone microarchitectural characteristics induced by osteoarthritis over time, Clinical Interventions in Aging, 7, 303-312, 2012. PDF

2011

Peng Kai Ong, Swati Jain, Bumseok Namgung, Yeon I Woo, and Sangho Kim, Cell-free layer formation in small arterioles at pathological levels of erythrocyte aggregation, Microcirculation, 18(7), 541-551, 2011. PDF

Peng Kai Ong, Swati Jain, Bumseok Namgung, Yeon I Woo, Hiromi Sakai, Dohyung Lim, Keyoung Jin Chun, and Sangho Kim, An automated method for cell-free layer width determination in small arterioles. Physiological Measurement, 32(3), N1-N12, 2011. PDF

Peng Kai Ong, Swati Jain, and Sangho Kim, Temporal variations of the cell-free layer width may enhance NO bioavailability in small arterioles: Effects of erythrocyte aggregation, Microvascular Research, 81(3), 303-312, 2011. PDF

Peng Kai Ong, Swati Jain, and Sangho Kim, Modulation of NO bioavailability by temporal variation of the cell-free layer width in small arterioles, Annals of Biomedical Engineering, 39(3), 1012-1023, 2011 PDF

Bumseok Namgung, Peng Kai Ong, Paul C. Johnson, and Sangho Kim, Effect of cell-free layer variation on arteriolar wall shear stress, Annals of Biomedical Engineering, 39(1), 359-366, 2011. PDF

2010

Bumseok Namgung, Peng Kai Ong, Yun Hui Wong, Dohyung Lim, Keyoung Jin Chun, and Sangho Kim, A comparative study of histogram-based thresholding methods for determination of cell-free layer width in small blood vessels. Physiological Measurement, 31(9), N61-N70, 2010. PDF

Peng Kai Ong, Bumseok Namgung, Paul C. Johnson, and Sangho Kim, Effect of erythrocyte aggregation and flow rate on cell-free layer formation in arterioles. American Journal of Physiology – Heart and Circulatory Physiology, 298(6), H1870-1878, 2010.  PDF

Peng Kai Ong, Dohyung Lim, and Sangho Kim, Are microfluidics-based blood viscometers ready for point-of-care application? A Review, Critical Reviews in Biomedical Engineering, 38(2), 189-200, 2010. PDF

2009

Sangho Kim, Bumseok Namgung, Peng Kai Ong, Young I. Cho, Keyoung Jin Chun and Dohyung Lim, Determination of rheological properties of whole blood with a scanning capillary-tube rheometer using constitutive models. Journal of Mechanical Science and Technology, 23, 1718-1726, 2009.

Bong Chung, Sangho Kim, Paul C. Johnson, and Aleksander S. Popel, Computational fluid dynamics of aggregating red blood cells in postcapillary venules, Computer Methods in Biomechanics and Biomedical Engineering, 12(4), 385-397, 2009.

Shatanik Mukherjee, Tae Goo Kang, Yu Chen, and Sangho Kim, Plasma separation from blood: The ‘Lab-on-a-chip’ approach, Critical Reviews in Biomedical Engineering, 37(6), 517-529, 2009.

Sangho Kim, Peng Kai Ong, Ozlem Yalcin, Macros Intaglietta and Paul C. Johnson, The cell-free layer in microvascular blood flow, Biorheology, 46(3), 181-189, 2009.

Sangho Kim, Peng Kai Ong, and Paul C. Johnson, Effect of dextran 500 on radial migration of erythrocytes in postcapillary venules at low flow rates, Molecular & cellular biomechanics: MCB, 6(2), 83-91, 2009

Sangho Kim, Shihong Yang, and Dohyung Lim, Effect of dextran on rheological properties of rat blood, Journal of Mechanical Science and Technology, 23(3), 868-873, 2009.

2007

Sangho Kim, Janet Zhen, Aleksander S. Popel, Marcos Intaglietta, and Paul C. Johnson, Contributions of Collision Rate and Collision Efficiency to Erythrocyte Aggregation in Postcapillary Venules at Low Flow Rates, American journal of physiology. Heart and circulatory physiology, 293, H1947-54, 2007

Sangho Kim, Robert L Kong, Aleksander S. Popel, Marcos Intaglietta, and Paul C. Johnson, Temporal and Spatial Variations of Cell-Free Layer Width in Arterioles, American Journal of Physiology - Heart and Circulatory Physiology, 293, H1526-35, 2007.

Bigyani Das, Jeffrey J. Bishop, Sangho Kim, Herbert J. Meiselman, Paul C. Johnson, and Aleksander S Popel, Red Blood Cell Velocity Profiles in Skeletal Muscle Venules at Low Flow Rates Are Described by the Casson Model, Clinical Hemorheology and Microcirculation, 36, 217-33, 2007.

2006

Sangho Kim, Marcos Intaglietta, and Paul C. Johnson, Newer Concepts of Oxygen Transport and Regulation: Relation to Vascular Physiology, Artificial Blood, 14(3), 79-83, 2006.

Sangho Kim, Robert L. Kong, Aleksander S. Popel, Marcos Intaglietta, and Paul C. Johnson, A Computer-Based Method for Determination of the Cell-Free Layer Width in Microcirculation, Microcirculation, 13, 199-207, 2006.

2005

Sangho Kim, Aleksander S. Popel, Marcos Intaglietta, and Paul C. Johnson, Effect of Erythrocyte Aggregation at Normal Human Levels on Functional Capillary Density in Rat Spinotrapezius Muscle, American journal of physiology. Heart and circulatory physiology, 290, H941-47, 2006.

Sangho Kim, Aleksander S. Popel, Marcos Intaglietta, and Paul C. Johnson, Aggregate Formation of Erythrocytes in Postcapillary Venules, American Journal of Physiology - Heart and Circulatory Physiology, 288, H584-90, 2005.

2003

Sangho Kim, and Young I. Cho, The Effect of Dye Concentration on the Viscosity of Water in a Scanning Capillary-Tube Viscometer, Journal of Non-Newtonian Fluid Mechanics, 111, 63-68, 2003.

2002

Sangho Kim, Young I. Cho, William N. Hogenauer, and Kenneth R. Kensey, A Method of Isolating Surface Tension and Yield Stress Effects in a U-Shaped Scanning Capillary-Tube Viscometer Using a Casson Model, Journal of Non-Newtonian Fluid Mechanics, 103, 205-19, 2002.

2000

Sangho Kim, Young I. Cho, Kenneth R. Kensey, Roberto O. Pellizzari, and Peter R. H. Stark, A Scanning Dual-Capillary-Tube Viscometer, Review of Scientific Instruments, 71, 3188-92, 2000.

Sangho Kim, Young I. Cho, Abraham H. Jeon, Bill Hogenauer, and Kenneth R. Kensey, A New Method for Blood Viscosity Measurement, Journal of Non-Newtonian Fluid Mechanics, 94, 47-56, 2000.

top