|2008||Ph.D, NUS Graduate School of Integrative Sciences and Engineering, NUS|
|2001||B.Eng (Hon), Chemical Engineering, NUS|
My research interest is to engineer biologically-meaningful tissue models that enable in vitro cell-based assays to be more predictive of human pathological conditions and drug responses so as to reduce current reliance on animal testing. The approach is to interface tissue engineering with microtechnologies, such as microfluidics and microarrays, to incorporate biological complexity into high throughput quantitative screening platforms. Tissue engineering enables the recapitulation of higher order tissue-level functions by controlling various physical and chemical cellular microenvironments, such as 3D architecture, extracellular matrix (ECM) and fluid-mediated mechanical forces. By miniaturising tissue engineered cellular constructs into high throughput screening platforms, we expect to capture more complex multicellular phenotypes and interactions to bridge between simplistic single cell-based assays and animal studies.